Courses
Search for courses listed in this bulletin. To find a semester course schedule (including instructors, meeting times and locations), go to mynmu.nmu.edu.
- Offered: Fall
- Graded: A/F
- Prerequisites: Entry into the Clinical Molecular Diagnostics Master’s program or instructor permission
This course provides the fundamental biological theory required to move forward through the Clinical Molecular Diagnostics graduate program. The course focuses on nucleic acid biochemistry, molecular diagnostic applications in a clinical setting, and career opportunities in the clinical sciences.
- Offered: Summer
- Graded: S/U
- Prerequisites: Admission to MS program in Clinical Molecular Genetics
CLS 516 is a one-week on-campus laboratory based course required for individuals who are completing a thesis. Students completing the non-thesis capstone or project option are not required to complete this course. Hands on application of nucleic acid based testing to include PCR, Real Time PCR, High Resolution Melt Analysis, LAMP based techniques, and identity testing.
- Graded: A/F
- Prerequisites: Admission to MS program in Clinical Molecular Genetics
Concepts and principles of current molecular technologies will be examined with applications to clinical diagnostics.
- Graded: A/F
- Prerequisites: CLS 520, CLS 536 and consent of the adviser
The techniques course will provide students with clinical molecular decision making strategies required for diagnosis, prognosis and management of human disease using techniques such as PCR, Real Time PCR, Sequencing, Microarray, and Isothermal Amplification Methods.
- Graded: A/F
- Prerequisites: Admission to MS program in Clinical Molecular Genetics or Doctor of Nursing Practice program.
Principles of human molecular genetics will be studied. The emphasis of the course will be on the molecular mechanisms and diagnostic methods of assessing inherited human disease, de novo genetic disease due to germ line mutations, and imprinting disorders.
- Graded: A/F
- Prerequisites: CLS 520
The course offers in depth molecular analysis for identification of cancer driver gene mutations related to cancer diagnosis and determination of disease state. Coursework includes review of cancer genetics and investigates molecular identification of hematological neoplasms, lymphomas, and solid tumors. Students will demonstrate mastery of subject matter via written and oral presentations.
- Graded: A/F
- Prerequisites: CLS 520
Course will cover technologies used in assessing inherited, somatic, and infectious diseases with an emphasis on massively parallel sequencing and the concepts in bioinformatics required to utilize sequencing data in clinical diagnostics.
- Graded: A/F
- Prerequisites: CLS 520
Course will cover applications of molecular testing in genomic medicine related to genetic identification. This will include paternity testing, identification of DNA in transplantation medicine, and analyzing crime scene evidence.
- Graded: A/F
- Prerequisites: CLS 520
Course will cover molecular techniques utilized in the diagnosis and prognosis of bacterial pathogens. This course examines the clinical evaluation of bacterial pathogens for molecular diagnosis. Students investigate the technologies used to identify bacterial pathogens using nucleic acid based molecular techniques. Students are required to determine the appropriate methodologies for identification of bacterial pathogens while demonstrating mastery of subject matter via written and oral presentations.
- Graded: A/F
- Prerequisites: CLS 520
This course examines the clinical evaluation of viral and fungal pathogens for molecular diagnosis. Students investigate the technologies used to identify viral and fungal pathogens using nucleic acid based molecular techniques. Students are required to determine the appropriate methodologies for identification of viral and fungal pathogens while demonstrating mastery of subject matter via written and oral presentations.
- Graded: A/F
- Prerequisites: dmission to MS program in Clinical Molecular Genetics
Overview of management principles and how they apply to the biomedical laboratory. Financial management, personnel management, regulation and accreditation of the clinical laboratory will be addressed.
- Graded: A/F
- Prerequisites: Admission to the MS program in Clinical Molecular Genetics, completion of a statistics course.
Overview of the research design and methods employed in clinical research, and the scientific writing method and style utilized to communicate proposals and research findings. Students will learn to critically evaluate published scientific literature and identify theoretical and ethical considerations in research design. Students will be required to assess scientific writing in the discipline and write a scientific research proposal.
- Graded: A/F
- Prerequisites: CLS 520 and CLS 526
The process of method verification and validation is an integral component in the implementation of molecular-based clinical assays. Course will provide guidelines for the development and validation of new types of molecular diagnostic assays.
- Graded: S/U
- Prerequisites: CLS 570 and consent of the advisor
Student will complete a laboratory based molecular genetics project such as a verification and validation study, assay design and development, or clinical utility study that will incorporate the knowledge and analytical skills learned in the graduate program. The project culminates in a written manuscript suitable for submission to a peer-reviewed journal. Selection of a study must be approved by the faculty advisor who will supervise the project. Appropriate forms must be completed prior to enrollment. The student should consult with the School of Clinical Sciences and the College of Graduate Studies for specific requirements. CLS 580 is offered in increments of 1-4 credits and may be repeated as needed to obtain the 4 credits required for graduation.
- Graded: S/U
- Prerequisites: Completion of a minimum of 23 credits of CLS 500 level courses or permission of Program Director.
Capstone course involving the evaluation of genetic and genomic technologies used in the diagnosis of inherited, acquired, and infectious disease. Students will be required to investigate and assess the strengths and weaknesses of genetic and genomic techniques using primary clinical research literature as an indicator of knowledge gained throughout the program and present findings in both an oral and written format. Students are required to pass a written program comprehensive examination modeled on a national certifying examination.
- Graded: S/U
- Prerequisites: Consent of the thesis committee
Student will develop a thesis with the help of a thesis committee. Appropriate thesis forms must be completed prior to enrollment. The thesis must be approved by the thesis committee and the College of Graduate Studies. The student should consult the department and the College of Graduate Studies for specific requirements. CLS 599 is offered in increments of 1-4 credits and may be repeated as needed to obtain the 4 credits required for graduation.